Published in 1965
• DUNE: PART TWO • THE MAJOR MOTION PICTURE Directed by Denis Villeneuve, screenplay by Denis Villeneuve and Jon Spaihts, based on the novel Dune by Frank Herbert • Starring Timothée Chalamet, Zendaya, Rebecca Ferguson, Josh Brolin, Austin Butler, Florence Pugh, Dave Bautista, Christopher Walken, Léa Seydoux, with Stellan Skarsgård, with Charlotte Rampling, and Javier Bardem Frank Herbert’s classic masterpiece—a triumph of the imagination and one of the bestselling science fiction novels of all time. Set on the desert planet Arrakis, Dune is the story of Paul Atreides−who would become known as Maud'Dib—and of a great family's ambition to bring to fruition humankind’s most ancient and unattainable dream. A stunning blend of adventure and mysticism, environmentalism and politics, Dune won the first Nebula Award, shared the Hugo Award, and formed the basis of what is undoubtedly the grandest epic in science fiction.
Select a screen adaptation to see a detailed comparison with the book

Paul Atreides, a brilliant and gifted young man born into a great destiny beyond his understanding, must travel to the most dangerous planet in the universe to ensure the future of his family and his people. As malevolent forces explode into conflict over the planet's exclusive supply of the most precious resource in existence-a commodity capable of unlocking humanity's greatest potential-only those who can conquer their fear will survive.
In the book, they spend a lot more time on worldbuilding
Film only covers first half of the novel
The timeline is different

In the year 10,191, the most precious substance in the universe is the spice Melange. The spice extends life. The spice expands consciousness. The spice is vital to space travel. The spice exists on only one planet in the entire universe, the vast desert planet Arrakis, also known as Dune. Its native inhabitants, the Fremen, have long held a prophecy that a man would come, a messiah who would lead them to true freedom.

Paul Atreides unites with Chani and the Fremen while seeking revenge against the conspirators who destroyed his family.
Most-voted differences from all screen adaptations
They provide a much more vivid picture of the park in the book.
The 2021 Dune film ends roughly halfway through the book, before Paul fully joins the Fremen.
They really spend a lot of time on setting

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